Dr. Joshua John-Ram SchacterDr. Joshua Schacter, DO FAAOS, is America’s Holistic Orthopedic Surgeon, with nearly two decades of surgical expertise.

Estrogen & Women’s Health

20 Sept 2025 · 0 min

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Short excerpt from a YouTube video by Dr. Joshua John-Ram Schacter titled "Estrogen & Women’s Health" (uploaded Sep 20, 2025). The speaker lists three estrogens—estrione, estradiol, estriol—and characterizes their relative proliferative effects: estrione described as strongly proliferative (may worsen cancer), estradiol as intermediate (can cause proliferation), and estriol presented as an "interesting option" for women with concerns about estradiol.

And estrione is really proliferative, so that's one of the ones that can cause cells to proliferate.
Estriol is also a really interesting option for women. You know, a lot of women, especially with the stigma around estradiol. So there's three estrogens, there's estrione, there's estradiol, and there's estriol. And estrione is really proliferative, so that's one of the ones that can cause cells to proliferate and possibly cancer to become worse. Estradiol is sort of in the middle, but it can cause proliferation.