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Everything you knew about HRT is WRONG 🤯

26 May 2026 · 1 min

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The FDA removed the black-box warning on estrogen-progestin hormones in November 2025. ACOG and the North American Menopause Society now say for most women, HRT's benefits outweigh the risks, especially when started within 5 to 10 years of the final menstrual period.

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Is HRT safe? Is it actually safe long-term? There's a lot going on, not just in terms of hot flashes, night sweats, and changes in sex hormones when we're talking hormone therapy, estrogen and progesterone. So one of the big shifts in official guidelines is related to hormone safety. It used to be only take hormones in the lowest dose for the shortest period of time for symptom management. But in November of 2025, the FDA removed the black box warning for hormones. So guidelines now from the American College of OB-GYNs and from the Menopause Society AI Mark, say for most women, the benefits probably outweigh the risks for hormone therapy, especially if it started within the 5 to 10 year window around your last menstrual period.