Longevity Fact Check: What Urolithin A Really Does to Your Immune System

Dr. Mark Hyman explains how urolithin A, a compound from pomegranates and walnuts that only 30-40% of people naturally produce, improved T-cell response and lowered inflammation in a four-week trial at 1,000 mg daily. He links mitochondrial decline to aging and recommends Mitopure as a tested source.
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Hey everybody, it's Dr. Mark Hyman. Now, most people think about their immune system only when cold or flu season hits. We start reaching for the zinc, the elderberry, maybe some extra vitamin C. All in an effort to boost our short term immunity. But what if we've been thinking about immune health all wrong? The thing is, our immune system is intricately linked to our longevity. And instead of seasonally thinking to try to boost it, we should be thinking about how to support it. And every single day. In fact, a recent study identified the brain and immune system as the two key biological systems most closely linked to how long and how well we live. Now, you might have heard me talk about inflammaging, the chronic low grade inflammation that drives so many age related diseases. But what most people don't realize is that inflammaging and immune aging, they go hand in hand. And that's because as we age, our immune system becomes less efficient at clearing threats and it becomes more prone to staying in a constant low level activation which fuels ongoing body inflammation throughout your whole system. Now here's where it gets even more interesting. Your immune system is one of the most energy hungry systems in the body. That energy comes from the mitochondria. These are the power plants inside your cells and there's thousands of them. So what happens when your mitochondria stop working? Well, well, your immune system gets tired. It becomes less effective at defending you from the threats and more prone to creating damage through oxidative stress. And over time, what happens? Well, that leads to an old sluggish immune system that fuels chronic inflammation and it accelerates the diseases of aging. Now, you know I'm a big proponent of targeting mitochondrial decline for healthy aging. And one of the most promising compounds to do this is something called urolithin, a big word, but it's a natural molecule that your body can make when you have the right gut bacteria to convert compounds found in foods like pomegranate and walnuts. The problem? Well, only 30 to 40% of people can produce urolithin A naturally. And that is where mitopure from timeline comes in. It's a pure bioavailable form of urolithin A that's been studied for over 15 years and published in top tier medical journals. Now, science has already shown that Uran A supports muscle and skin health. And now for the first time, we're seeing evidence that it may also support a healthier, more resilient immune system. A new clinical trial in healthy middle aged adults found that just four weeks of supplementing with 1,000 milligrams of urolithin A, which is what I take every day, led to a more youthful immune profile. T cells became more responsive, the immune system got better at clearing threats, markers of inflammation. They all went down. All while mitochondrial energy production proved across the board. In short, uran A helped the immune system act younger, faster and more efficiently. Sounds good to me. Now as we continue to learn more about the link between mitochondrial health and immune resilience, compounds like urolithin A are opening up new possibilities for how we think about aging. Supporting our immune system isn't just about avoiding your next cold. It's about laying the foundation for long term health for energy and vitality. And that's why my choice is mito pure from timeline. I take it every single day because not all urolithin A is clinically tested and third party certified. If you're focused on longevity like I am, this is something worth paying attention to. If you love that last video, you're going to love the next one. Check it out here.
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