Why Omni Biotic? Presentation 2022

Thank you so much for inviting us here. It's really wonderful to have spent all this time with you. We're going to talk a little bit about omnibiotic today. I'm going to go through a little bit of background about the brand, how the brand got here to the United States, some of the clinical research behind it. And then the good stuff is going to come from Dr. Nicole here and she's going to explain several of her cases using the omnibiotic formulation. Omnibiotic has been in Europe for about 25 years. It is the leading probiotic in northern Europe. Specifically. These probiotics are quite a bit different than what you'll find normally on the shelves here in the United States in that they're function focused and evidence based. We'll talk a little bit more about that in a moment. Since 2019, 2019, they've been here in the United States. A German family actually brought them here based on their own experience. So dad had gut and liver problems, daughter had Lyme disease and the other daughter had psoriasis. So they all used different formulations and had tremendous success and they made it a family business. So they are a subsidiary of the Austrian Institute Alergossone and they are Polarisan usa and we have five formulations currently here in the United States. So just really briefly, I'm going to go over this very quickly. The gut microbiome basically impacts everything. This is not just a digestion benefit, the gut immune system. Most of your immune system is in the gut. More than 70% is in the adult gut associated lymphoid tissue, the gut brain access. More than 90% of your serotonin is generated in your gut. Gut liver is something that we don't talk very much about, but it has a very direct impact. The bugs in your gut and your liver and detoxification, as well as your skin and your gut microbiome changes over time. So very quickly I'm going to put there are links to the articles that I reference here. The slides are a little bit dense, but I wanted to make sure that you have the background if you wanted to read a little bit more. So it's fairly well accepted that probiotics, if they're done properly, are just a wealth of health, but they are dependent on the mechanism, meaning that these probiotics.

Must be live bacteria.

And each strain, meaning you have a genus, a species and a strain, has their own strengths and powers. Let's say you can think of it as dog breeds, right? So you have a little Chihuahua and a big Irish Wolfhound, they're the same species, but clearly they're different beasts. That's the same thing with strains. We also, the way omnibiotic does this is that they formulate four specific indications. So we understand what all of our strains do. We have a library of them and we formulate four specific actions. So we have a gut brain formulation called stress release that really works on the gut brain access. It improves mood, mind, thought clarity. But we also want to make sure that the probiotics actually get through your gut, get through the acid in your stomach. We do this testing through an artificial gut system. So we are very confident that our products actually get to the location that they need to be and do their activity. And then we also do actual human clinical trials. The way this brand attacks evidence is very much in line with a drug. So it's sort of a mini drug development program. Manufacturers are not required to do this, but we feel like this is essential to make sure that our products are performing as we wish. This is a little chart about survival through the gut. So when the products were initially being developed, we looked at different dose delivery forms. So capsules versus tablets versus powder. What we found was that regardless of the capsule type, that once they get to the gastric acid, they were not surviving all the way to the intestine. The hypothesis was because these bugs would initially hit acid, a very, very hostile environment, so they were not recovering when they wake up from their sort of freeze dried state. But the way we do it is we put the powder, the probiotic powder, in water or some other non acidic liquid, let it wake up. That's why we have you wait for about a minute or so and then you drink them. So the carrier that the probiotics are in contain nutrients specific to the strains in the formulation. So we know they get through the acid in the stomach and arrive in your intestines alive and metabolically active.

We're going to talk a little bit.

About a few of the functions that we focus on here. For amibiotic one is mood by microbe. So this is the gut brain axis. It's pretty well recognized at this point that psychobiotics or probiotics that focus on the gut brain axis are a really promising aspect of psychological and psychiatric necessary medicine. And we tested ours. So initially this one's my favorite formulation because gut brain axis really, really excites me. So this first study is all self report. So these are healthy individuals, over 30 days reported a more positive affect. So more positive mood, less vulnerability to depression like hopelessness and Rumination and they also reported significantly improved memory and positive responses to negative stimuli. But this is my favorite. They also our company also looked at fmri. These studies are done at the University of Braatz. And what they found is over just the 30 days with no other type of intervention, that people taking the stress release psychobiotic had less activity in the default mode network. So that's more internal stimulation, that's more rumination, that's really associated with depression and depressed states and more activity in the Salience network. So this is associated with external stimuli and confidence and decision making and executive function from a probiotic 30 days. Amazing. The liver dysfunction is also a big problem for us. After two years of staying home and eating badly and drinking a little too much, it really brings the liver to the forefront. The liver and the gut talk to each other constantly. They have the portal vein. That's a direct communication road, a highway. If you have a poor gut health, you'll have leakage of toxins, toxic overload. It's a real problem. And there is a recognition that microbiome focused efforts can really improve the state of the liver. We did clinical trials on this product as well. This is omnibiotic he talks, the gut liver focus. And we know several folks that really like the he talks. What we found was with cirrhotic patients, they actually had improvement in liver function, which is astonishing because we don't really have any pharmaceuticals or other therapeutics that do this. And this again is only the addition of Ketox. No other changes in diet, no other changes in medication. And the infection rates here were very low. So these are cirrhotic patients. We also have studies in type 2 diabetes. So these are newly diagnosed diabetes patients that are medication naive. So they're taking no medications with whatsoever. The study only included the addition of he talks. This was over a longer period of time, so six months. What they found was a reduction in Homo ir, improvement in hip waist ratio, lowered inflammatory markers from the addition of just a probiotic. There is also the issue of pathogens. We have a formulation that's focused on gut restoration. This is really important for things like antibiotic use where your gut microbiome becomes very disrupted from the use of the antibiotic. This particular formulation, this is AAD in Europe and AB10 here in the United States. We looked at colonized drug resistant gram negative bacteria colonized patients in long term care facilities and found that the pollination was reduced by almost half at eight weeks and even more at 24 weeks. So we're getting close to 70%. We also looked at this same formulation, the gut restoration formulation, in nursing homes for antibiotic associated diarrhea, and saw significant reductions regardless of the antibiotic used. And the good stuff is now with Dr. King.

Thank you so much for having me. I'm here probably like many of you, because I was looking for hope in feeling, suffering in anxiety, depression, body pains, headaches, gut upset, and I was looking for hope. And that started my own journey in trying to prove to myself that you can actually heal. And so throughout my practice, I've been working with patients for over a decade. And not too long ago, I came across omnibiotic, and it's been absolutely transformational, and I'm so excited about it. And so when I had the opportunity to come and just share and talk about it, I was really, yes, Deb's absolutely on board, so that's why I'm here. And I have some really exciting patients to share with you. So the first case is Amanda, and she's 12 years old. And I've been working with Amanda for a pretty decent amount of time. She had a really stressful entry into this world. Difficult labor and delivery, and there was a lot of trauma that came with that. She, her mother had an emergency cesarean section, and then Amanda had to be helicoptered to a neonatal unit. So right off the bat, we have high stress, high amounts of cortisol, and we're not getting that vaginal bacteria and the skin to skin bacteria and that nervous system attenuation that is ideal when coming into the world. And so she entered the world in quite a stressful way. And so she's going through life and she's been described as a colicky baby and a moody baby. And so. So they're doing everything that they can. Conventional medicine has offered her the best that they can come up with to try to calm her stomach, support her mood. And she was really struggling. And at one point she was taking omeprazole, which is for your stomach, for stomach upset, acid reflux, and it wasn't really helping. She still had a lot of stomach upset. And she was also on an antidepressant and she wasn't getting better. And in fact, she started to develop more social anxiety. She was withdrawing, she was really timid. And so we started working together and we've done lots of things together and she's seeing improvements, but there was always this piece of the puzzle that wasn't shifting. And so we decided to work on the gut brain access in a lot more detail. And with this product That I read quite a lot about the functional MRI that you were describing were really compelling to me. And there's a lot of research in the safety of psychobiotic use in kiddos. And so I was like, let's try this. And she did really well. I selected stress release in particular because she has this gut brain, gut anxiety picture with the gas and the bloating and the colic and the indigestion, and then this timidity and this anxiety and this lack of confidence and missing skills. And it felt like a really good fit. And so we gave that to her. And so you see here on this slide how she did on stress release. And I get a little bit emotional talking about it, because if she hadn't have had the opportunity to do deeper digging, if she hadn't had the chance to learn about healing her mind and her gut and doing something so simple as taking a little bit of a probiotic and some water, which was very tolerable for her. Remember, she's 12. You can't give her handfuls of pills. Oftentimes, our adolescents are quite reluctant to do that. And she did well. So you see that her appetite got better. She was able to gain a little bit of weight, which was such a victory. Her digestion got better, her stool was more formed, she had less gas, she had less bloating, her stomach pain significantly better. She was so happy. She was actually reaching for her omnibiotic in before going to bed at night. She knows it makes me feel better. She was going back to school. She was interacting more with people. And even the interactions that she and I had were significantly better because now I'm associated with this stuff that works, that makes her feel better. And the teachers reported she's better. So I'm really on fire for this. I'm still excited. And so again, I've been looking for hope for people, and this is an example of hope. It's really cool. This is a little bit more of a complicated case. This is Susie. She also has gut anxiety. I always teach people that there are eight main types of anxiety. And our bodies, when they develop symptoms, they're trying to show us that they need support. There's an unmet need. There's something out of balance. And the job of the doctor, the job of the healer, is to listen to those signals and to help give the body what it needs, because you are. Our body can heal itself. Sometimes it just needs a little bit of extra tlc. Right. So this is Susie. She has a very complex history of chronic disease. She had breast cancer. She had Graves disease. She had an oophorectomy where they took out one of her ovaries. And she also had an appendectomy where she was having a lot of gastrointestinal distress. And they removed her appendix. She was also taking, of course, because she had no thyroid, because of the Graves disease, they removed her thyroid. She was on long term thyroid medication. She was also on a couple of other prescriptions. And when we were working together over time, there were a few things that we were really able to nail and that were really getting better. For example, we identified with genetic testing that she really struggled with certain detox pathways. And so her body was building up a lot of toxins. And so as we worked on the detox, she did really quite a lot better. But there were two pieces that weren't shifting the way we needed them to. She had the gut anxiety. She had a lot of gassiness, bloating, constipation. But her main thing was the anxiety. She felt agitated, restless. The anxiety would often come out at snapping at her spouse. And she didn't want to be irritable with her spouse. It was just overwhelming and it just burst out of her. So if you felt that way, if you felt that way in conjunction with feeling upset in your stomach, then this might be a great solution for you. So I took some baseline testing because at my root, I am a scientist, I am a diagnostician, and so I like to see things being proved with the science. And I'm really grateful that we actually were able to do some stool analysis testing. So when in doubt, do the functional testing. Cause it can take a whole lot of guesswork out of your protocol so that you don't feel like they're starting spaghetti at the wall, giving you just a bunch of supplements and hoping something sticks. We were able to identify a little bit of the why she felt the way that she felt. So you see here two things. One is you see some screen captures from her stool analysis results, and then you see an anxiety scale. I want to start with the anxiety scale. The one thing that came out for that is that she said, Dr. Nicole, I didn't actually realize how anxious I was until I took this test. And I was like, yeah, well, now we have a baseline and let's look at your gut and see what the heck is happening there. And so we have a few things that showed up. And so you see in the green column, these are beneficial bacteria. They are important to make you healthy, to feel good in your body. The bugs in your gut. I don't know if you know this, but they regulate your immune system. They regulate your neurotransmitters, they regulate your endocrine system. The gut bugs in your gut regulate everything. So she has this history, this history of autoimmune, thyroid. So we wanna know what's going on with the immune system. We have this history of mood dysphoria, what's going on with her neurotransmitters. And so we wanna look at the root cause. And for her, a lot of it went to the gut. So then you have in the yellow column, commensurate bacteria. And what's really neat, here's a little fact about your commensal bacteria, is that you inherit a lot of this. And so when we, Amanda, just a moment ago, who had this emergency cesarean, she didn't get a good delivery of these bacteria. And if you've been on antibiotics or other medications, steroids, gut medications, all of this can affect your commensules. And so we saw some areas of improvement there. And then in the red column, we see dysbiosis. And so dysbiosis is a lack of microbial diversity. And she also had excessive amounts of a pathogenic bug called Klebsiella, which we know can cause symptoms of digestive upset. So that was really interesting. She also had high amounts of secretory iga. Secretory iga, we'll talk about on the next slide, is associated with immune system activation, especially in the gut. And she had high levels of calprotectin. And again, that rises when there's a lot of inflammation. So now we have a little bit of evidence and we have baseline testing, because when we add a protocol, we're able to look at how she feels subjectively. But then I also want to know that it's not just placebo and is going to come back. I want to know that we're getting actual objective improvements. And the really neat thing is omnibiotic, if you didn't know, has a Psychology Today blog where so much of the stuff that Pam and I are talking about. If you're like, I need to know more, then definitely check out the Psychology Today blog. I have a screen capture here of an article about inflammation and the relationship between inflammation and mental health. And so we do see that Susie has a ton of inflammation going on as measured in her stool testing. And we know that there's a lot of emotional dysfunction, anxiety, irritability that she really wants to feel better from. And it's very likely that inflammation could be playing a part of that. So we were also diagnostic and scientific in that we made one change and I'm super grateful to have this kind of flexibility. And a patient was like, you want to do one thing? I have this idea. We put her on stress release. I picked stress release because the main thing of the main thing is the gut anxiety, the digestive upset and the emotional symptoms. And so let's see what happens. You ready? So in 30 days she was significantly better. But I have to tell you, I got an email from her two days after starting the stress release and she was like, Dr. Kane, oh my God, I love this stuff. Her gas and bloating was gone in two days. And Pam was talking about this earlier, about how with some of these products by omnibiotic that you can actually see results pretty quickly. I generally tell my patients, give it about a month because you gotta just make sure that the bugs are integrating, that they're kind of joining into milieu, making friends. So give it a little bit of time. But for this case, she was remarkably better. Two days, gas and bloating gone. We also in 30 days repeated her HAMA scale and you see that she is significantly better. All those black dots, they were all mixed up on the right side and visually you can see that they're going to the left side where we don't have as much anxiety. And I did, I did do a side by side because I'm a very visual person. So I wanted you to be able to see this too. Anxiety scale improved by 48%. And we repeated her stool testing. So you ready for this? This is the coolest part for me. So I used a more advanced stool test for this. This is a Genova test and we measured all of the same things and then some. So here's what we see. So if you look at this screen capture that I have here is her SIGA levels were significantly reduced in 30 days. Okay. Her calprotectin levels, remember that marker of inflammation resolved. That is incredible because generally before finding omnibiotic, I was using all sorts of different supplements. I was using anti inflammatory powders, glutamine. We kept it really simple and still got great results. Because, you guys, we're giving the body what it needs to do the work to heal itself. And your body is able to heal itself. And sometimes it's just a matter of listening to what your body uniquely needs. And this worked for her. Her dysbiosis, her imbalances were resolved. And you can see that when you look at the vertical columns is Genova's really ne in that it will actually tell you what components are out of balance and then suggestions of what to do with it. And as you see, these markers are all significantly better. So the plan was to continue the probiotic because, oh my gosh, it worked so well. Don't stop. She was like, can I take it twice a day? Sure, do it. See what your body says. And then we wanted to do cleansing because we do have this genetic trait where she doesn't detox very well. So in conjunction, we're removing obstacles to cure and we're giving the body what it needs. And she's, she's doing great. Since I did this whole presentation and put together this data, she still continues to rock and roll it and she loves Omni. This is a 14 year old male and he has a diagnosis called ARFID. And what it is is it's a type of eating disorder where the individual has had an adverse reaction to eating food.

Food.

So if you are or have somebody in your life who is characterized as a picky eater, or they're really sensitive to textures, or they're really restrictive and they'll only eat things prepared certain ways, then it could be that their nervous system is just simply having an adverse reaction to food. And we can actually work on that with the gut, which is so fascinating. And this is a really great case. He was tricky to treat because the ARFID made it difficult for him to swallow pills. He was very limited in his nutrition. Getting him to eat anything outside of his four main food items was nearly impossible. He'd worked with psychiatrists, dietitians, he'd worked with naturopathic doctors. He'd done all of the things. I've been working with him for quite a long time, oftentimes feeling like we're hitting our head against the wall. And so now I'm discovering omnibiotic and I'm like, I wonder if he could tolerate this because now we have a very particular and picky consumer. So if he could tolerate it, then probably almost anybody could. So I just want to tell you a little bit of just sort of objectively what he came in with. So he had low weight, he's 100.5 pounds, he's 5, 6. He's a very tall, lanky young man and he had a lot of headaches. He had eczema, bright red eczema patches. He was probably allergic to sensitive, reactive to wheat because that was almost everything that he ate was wheat based. And you can't take that away from him. Because then he would be eating nothing. So we can't do much in terms of dietary modification. We just gotta try to add and support him. And he had a lot of nausea. He would wake up every single day nauseated, probably because he's inflamed and he has low blood sugar and he's not eating. His stomach's upset. So I added omnibiotic stress release. He's nauseated every morning. He has digestive upset. He has this reactivity to eating certain foods and he has this anxiety and he's sad and he's angry. And so I'm like, all right, gut brain axis stress release it is. So we had him continue everything else he was doing. We added the stress release and then we checked in. In 30 days, he'd added chicken fingers to his diet. I'm like, yes, we're getting some protein in this boy. He was able to swallow it down. And he actually said, I like the powder. I almost cried because I was like, thank God he likes the powder. So he would actually take it. And he was. He gained one pound, which is again a huge victory because this poor guy, he'd just been growing taller and taller and getting skinnier and skinnier because he was so calorie restricted. He was sleeping better, his nausea in the morning was better, his mood was better. I'm a believer, like after all these cases, I'm like, everybody, let's just put this in the water. Everyone needs stress release. Pumped. Let's talk about this beautiful soul. This case is very near and dear to my heart. I care so, so much about this person. And she has a really strong history of abuse, post traumatic stress disorder symptoms. And she had seen a lot of doctors. But what was especially challenging about her case is she's incredibly intellectual. And when she was looking at treatments through the lens of trauma and grief and depression and self hatred is she would often use treatments as weapons against herself. So if you teach her cognitive behavioral therapy, she'll use cognitive behavioral therapy as a weapon against herself. So she was really stuck. Doctors tried antidepressants, she became suicidal, they tried mood stabilizers, she became a zombie. They tried gut work on her, they tried low dose naltrexone. Like if. If it was existing, then she tried it. And she'd done a ton of counseling, a ton of CBT work. She'd worked on the trauma, but she couldn't really get into the trauma very effectively because she had no effective tolerance. If something came up, she was to going already so dysregulated that if Anything came up, it made it 10,000 times worse. And so we couldn't really do a ton of trauma work. It was kind of like a filibuster. We were stuck. And so we. She'd also had a lot of physical and health issues. And at the time where I was starting to focus a little bit more on Omni products, getting really excited, wanting to give them to everybody. Her main thing of her main thing is I can't even begin the process of working on my trauma and healing unless I stop getting sick all of the time. And so if she would go outside, she would get sick. Cold air would make her sick. Seeing her niece and nephew would make her sick. She would end up with sinus infections, get an antibiotic, she would end up going and getting gastroenteritis and having lots of diarrhea and get an IV and another antibiotic. So part of my brain is thinking, ooh, I want to give her stress release. But when you're looking at what's going on with you, you want to look at the main thing first. Think of it like an onion. On the outside of the onion, maybe it looks purple and maybe that's the main thing for you. And then you treat that and then you'll pull that layer of the purple off and then maybe underneath it's more purple, but maybe it's green. And that green may represent a deeper layer or something else. And so for her, if we're looking at the main thing is she has immune system dysfunction, she's taken a lot of antibiotics, she's constantly getting sick. So I wanted to start her on a probiotic that would get to that, replenishing her gut bacteria, really supporting her immune system. So we gave her AB10 and I didn't see her for four months. And typically when I don't see someone for four months either they're despairing and it didn't work and they're very sad and they just didn't come back, or they're like happy as a clam and they don't call me. And so I'm like hoping and hoping. So then I was actually talking to Pam and Pam was asking if I'd had anybody using AB10 and I was like, let me check in on her just to see how she is. And she wrote me an email and she's like, oh, I've been doing great. I was like, well, I'm really happy to hear that. And so this is. We did a follow up visit. It was four months later. She's still taking the AB10. And then I have a quote of what I transcribed that she said. So I started the AB10 May 9, 19th, four months ago. She said it seemed to really help. It's worked better than any probiotic I've taken. When I first started it, I noticed that I was more physically healthy, feeling my digestion was better. And she had been on a sugar kick for quite a while. And she found she was able to curb those cravings, eat less sugar. She also was hooked on Excedrin. She was having a lot of pains and inflammation, and the Excedrin seemed to really help. And so that had been a real struggle for her. And so she's telling me I was able to taper down, reduce my Excedrin dosing. So she's objectively feeling better and med tapering, which is huge. And she says it's helped me not get sick. I haven't had any yeast infections either. So now we have this person. And all she did that was new or different is take a probiotic that has all of these delicious, active, wonderful bugs that actually stimulate your body to heal itself. And she stopped getting sick, and she had been sick all the time. And so if you're feeling like I get every single thing, there's a pandemic. And so if you want to protect yourself and support your immune system, even if you haven't been sick and you just want to be healthier, I'm obsessed with AB10. It's really good. And what's the. So interesting, if I can interject about the anxiety piece, is that there's actual research on specific bacteria's ability to attenuate neurotransmitters. So some bacteria are really good at making serotonin, and some are really good at making dopamine. And so that's incredible to me that we have that technology to assess that. And then there's more research on how. And this is like your zone of genius, but there's more research on how they function together. And I think that's what makes Omni really quite different, is that they've studied how the bacteria actually function together, because some products, it's like, well, this one works really well at making serotonin. And I'm just gonna throw it in with all these other probiotics. But we don't actually know if they get along nicely, if they're synergistic or maybe they're antagonistic. But that's really cool about the anxiety and depression piece, is if you do testing and you're like, I see evidence that they really need more dopamine. And so then maybe you start thinking about probiotics that have been studied to increase dopamine or GABA with anxiety. What are GABA producing? Bugs. And then the research on how they can actually work together synergistically to give you the result you want.

And that's why we do the research to make sure that our assumptions that these are going to synergistically work well together for the desired outcome happens. Because, you know, these bacteria are actually intended to be antagonistic against some other bacteria, the bad bugs. So we take the theory and prove it out in the clinic.

So in the powder, when you were talking about, they contain nutrients specifically for those. So are they prebiotics or more just nutrients?

There is some prebiotics. So in all probiotics they're lyophilized, so they're freeze drying. The idea with ours, the way we deliver it is that they get woken up in this beautiful soup that contains vitamins, some vitamins, some minerals, some prebiotics specific to the strains that are in the formulation. So they start working right away. And a lot of our practitioners will have people swish it around in their mouth, some for thrush. They'll have them put the powder right on the tongue to really reset the oral microbiome so you have activity all the way down the pipe.

That's what I do.

I brush my teeth, squish my mouth and hold it there because, yeah, I believe that our mouth microbiome is also. And I like the drink because you can leave it and other capsules. You really miss the mouth microbiome.

Yes. And honestly, they're not alive. We thought we were going to put our probiotics in capsules, tried every capsule and then thought, why isn't this working? We tested many different competitive products in different capsule types and they're dying off because they sit in acid before they get to where going. So a lot of these brands were less than 10% recovery through the artificial GI system, where the way that we deliver it is about 85, 87% recovery. So you have active the bugs that are supposed to be working for certain conditions. They are there, they're working.

I saw that.

You know it in the formulation there's like bicarbonate. So is that the idea is to kind of make the environment less acidic as well, so that when you're consuming, it's not like, you know, killing off the microbes?

Yes, but because they're alive when you're taking them, because we let the probiotics sit in the water for a little bit. They're metabolically active already and their human source strength. So, you know, they're accustomed to being in your body. They're alive, they're awake, they're doing their thing already. So they have a higher life. And that's why we ask people to take them on an empty stomach as well. You want it just to kind of go through as quickly as possible to make sure you get that very strong recovery.

Have you done any studies on like stress release anti talks together by any chance?

Yeah, we don't have any clinical trials on that, but we have an awful lot of people that will do a few different formulations. You asked about balance and that's more kind of a general maintenance for the microbiome and immunity. But it works great for people who suffer with constipation. So these constipated people maybe are stressed too. Right. So they'll take their, you know, the balance in the morning and stress at night or he talks at night. I know that you use it for sleep, you know, people that struggle with sleep. So, you know, probiotics are super safe. We do not put in 100 or 200 billion colony count because it's not necessary.

It's really not.

You know, the other formulations that have such a high count, it's because they're not. You don't have active probiotics that are getting to your intestines. So our formulations are between 5 and 15 billion. They're clinically validated. So we know that dose is effective towards these specific outcomes. But you can take more than that. These things are very, very safe.

Thank you so much.

Thank you.

I have one question for the listeners out there. What if somebody doesn't want to change their diet and their diet is causing.

Inflammation and gut dysbiosis?

What would they do? Would they take this product and that would have.

What would you recommend? Well, what's really interesting in one of the cases is that this person was eating a bunch of sugar and she was able to cut back on the sugar. And then once her chemistry changed, then it became easier and more natural.

So some of the functions of these probiotics are that they'll tighten the proteins in your gut to make sure that you're not leaking out a lot of toxins. And they will get rid of the pathogens that are in your gut that are saying, feed me, feed me a Big Mac. I want some French fries. So you're going to be balanced with the good bugs that prefer to eat salad. So it Kind of goes hand in hand. Yeah.

I think that also plays in like yeast overgrowth. Yes.

Take these.

Absolutely big on sugar cravings. So when you see a decline in sugar craving, it's because the probiotic is crowding out the yeast overgrowth.

That's absolutely wonderful.

Yes. Which is so nice that you're mentioning yeast because yeast is such a huge problem. And so a lot of clinicians will just go straight for killing the yeast. But if you just eradicate the yeast, you still have the environment that housed the yeast. And so that causal factor hasn't been addressed versus if you just give them the happy, delicious good bugs that will crowd out the yeast you're supporting and giving the body what it needs while also removing the obstacle to cure. So it's just so beautifully poetic.

But diet is important. You know, preferably you eat high fiber foods that feed the good books and not highly processed, high sugar content food that feeds the bad bucks.

Yes. I'm sorry to tell you that, Paul.

That was the general audience.

It was for a friend. I'm asking for a friend.

Speaking about diet, I know that depending on where you live in the world, you've got to change. Now, is there any correlation between the type of probiotics that you should take.

Per.

Type of diet that you intake or type of place that you live in the world?

That's a really interesting question. So the question is about depending on what you're eating or where you're located, should the probiotic change with respect to that? And I have a sort of like serpiginous answer to that. And so there's this really interesting study that was conducted and they looked at an indigenous tribe and they lived off of primarily rice and beans. And they looked at the health markers, so like blood sugar and insulin and micronutrients and iron and all of these measures of health. And they found that this particular group of people were for all, all intents and purposes healthy. They didn't exhibit any deficiencies. And so they're wondering, okay, what is that about? Is it the diet? Is it the health? Is it their bugs? So they took people from volunteers in the United States and they fed them that exact same diet. And they did pre measures and then they did post measures after consuming the diet. And they found that those individuals ended up with deficiencies. And so what we see is that in a state of optimal health, that the body is incredibly adaptive. And so while diet and nutrition is really important, that in a state of wonderment that in a state of optimal health that your body can pull out the nutrients that it needs, when it needs it from the food that you're eating. And so for a lot of people, I really encourage them is just nourish your body, give your body what it needs, and then allow it the opportunity to pull out all of the ingredients from what you're eating.

The other thing to keep in mind is that, as you may know, most of the bugs in your gut are obligate anaerobes, meaning they can't be exposed to oxygen, it kills them. So probiotic manufacturers can't really produce these as probiotics. So we have a very limited number of bugs that we can operate with and make probiotics. But the thing is that these Lactobacillus and bifidobacterium, the metabolic waste products, basically short chain fatty acids and other things, make the environment in your gut very hospitable to healthy bugs. So you can just put probiotics into your gut that only have lacto and bifido. But if you get your stool tested afterwards, you will have much more diversity, far beyond what you're putting in, because you're making the gut environment hospitable and a warm, friendly place for the good gut bugs. And we do have some actual studies on that. It was fascinating. Like, where did all the other things come from? You know, you're just making the environment proper for the healthy bacteria.

I just want to also add, like, you know, we talk about it's the terrain of the whole gut microbiome. The world itself is getting more exposed to the processed foods that we're now consuming. So it's not just like what you eat anymore, right? Because like, there's the whole industry of the food products that are out there that are impacting and destroying the gut microbiome. So introducing any probiotics that enhances the terrain of the gut. Microsoft microbiome. It's the strain that enhances the growth of other strains that you cannot get from probiotics. So I think that's what probiotics can do, is that it enhances the growth of other bacteria and then it's their postbiotics, it's the nutrients that you cannot get from food itself. We only are limited to knowing, like, oh yeah, all these nutrients are important, but a lot of the nutrients is produced by the microbes that we're not aware of. But now there's a lot of research going into, like the postbiotics and its impact on health. And it's what's controlling and regulating our immune system is the nutrients or it's the bacteria waste products, but it's nutrients to us.

Exactly.

So, yeah, brilliantly said.

Yeah.

In regards to, when we talk about hereditary diseases that people have, should you, like if your mom has cancer and your grandparents had cancer and stuff like that or some other disease, and we talk about like balancing the gut microbiome, is there something that you should be doing as precaution? Just like making sure that your gut microbiome is balanced in an optimal state per what's going on in your family.

With consideration to risk factors. Inherited genetics, like family traits, dispositions, is what can you do to make sure you're checking all your boxes to be optimally healthy, especially as it relates to your gut bugs. Right. And so if you were my patient and you were coming in with that question, I would. The pillars of health, I would focus on the pillars of health, make sure that you're removing obstacles to cure. So detoxification. Are you in relationships or in an environment that is an antagonist to your well being? I think about is there any sort of epigenetic or emotional trauma that could be causing disease attunement in your nervous system and in your body and doing the deep inner work with that? So, and then we think about, okay, genetically what might be going on. And so I like to do genetic and epigenetic screening. And that's really important because then if you have a cog that isn't working properly and then there's a pathway that isn't detoxing or methylating or whatever it is that, that involving that you can head it off before enough accumulation of problems occurs and a disease develops. And then doing periodic stool and organic acid testing I think is really helpful. And so I love Genova and they have a really comprehensive stool test so that you can see like, oh, this last year I've been seeing elevations in calprotectin. Something's making me inflamed. We know inflammation underlies a lot of disease. Cancer related, immune related. So let's get to the source of that. And then organic acid testing is more epigenetics. Okay. Am I making serotonin metabolites properly? Am I processing ketones properly? My amino acids. So the pillars of health, annual testing based on risk, risk factors. And I think you're gonna do incredibly well. Yes. Did you have to add to that?

Nope.

I think you did a great job.

I love that question. That's because we all want to think of, we want to be empowered. And it's like my whole thing is like having hope and so Genetics is only like, I heard this quote and I should fact check it. But genetics, it's like 10% of our healing journey. So so much of it is our environment and our internal environment and our nutrition and all of those things. Detoxification is huge. And so being empowered and having hope and not allowing that genetic trait to write your story for you, like you, doc, were talking about having that blank canvas and like, I'm going to choose how I'm going to make my choices with my life and my health so that I can have the joy that I want. Yeah.

The genetics are more the risk. Right. It's risk and potential. What you do with your genetics is what your life is going to look.

I just want to add to what Dr. King is saying is like the epigenetic piece that is the determining factor, the genetics. We all have risk factors. We all have mutations in our genes, but it's the environment that this gene is in that gets either turned on or turned off. And what you were pointing to, your question, you know, the risk factors we have is there. There are studies now that show that toxicity can be passed on up to four generations. So whatever your great great great grandmother had, you actually carry it within yourself. But it's only turned on if you live in a toxic environment. So that's why detox is important. Diet and then, you know, relationships is important because relationship is actually like core to our being as human beings. And when we're in toxic relationship, it turns on the genes to produce inflammation. So it's, it's all of like, it's, it's all of it. Right. It's not just like one thing you can do, but it's like, how do you live your life? What do you surround yourself with? If you have a thriving environment that empower you, then you will thrive. And then if you have a toxic environment, then your genes will turn on certain genes and make certain proteins that basically make your body sick.

And those stressors will switch your HPA axis. So how you react to stress and it feeds on each other. And actually good gut health, good gut bugs can reset that point, that HPA set point. So you don't have real high reactivity, stress reactivity. It's really amazing.

And what we're finding is like, it's.

Our perception of stress. Yes.

How you perceive it, it could be stressful for some, but if it's not stressful to you, it doesn't impact you or your genetics. But if you let it impact you, then it will turn on your genetics. So knowing these things. The awareness of you having the power to actually impact your own genetics is very powerful, and I think people should know to use that as a tool to empower your own health and your own healing.

You're not helpless. Not. Yeah.

Oh, I love that. That's so good.

Awesome.

Any other questions?

No, I. I love it. I feel empowered already.

Yay.

Yes. Thank you for having us. This has been fun. Thank you.

Thank you for being here.

Thank you.