#453 My MDMA and Psilocybin Journey Unpacked - With Mike Zeller

18 Mar 2026 · 71 min
Episode

18 Mar 2026 · 71 min

0:00

In this episode Mark Groves interviews neuro‑rewiring expert Mike Zeller the day after they completed a combined MDMA and psilocybin‑assisted Internal Family Systems (IFS) parts‑work session. The conversation weaves personal narrative, scientific background, and therapeutic protocol. They describe how the medicines create a physiological opening that allows frozen, trauma‑laden emotions—often locked in the amygdala—to be accessed, processed, and integrated through parts work. Mike explains his evolution from NLP and peak‑performance coaching to trauma‑focused neuro‑rewiring, emphasizing the role of nervous‑system reset, neuro‑optimization (NAD, creatine, omega‑3s, hormone testing), and breathwork. A detailed case study of Mike’s wife illustrates rapid remission of complex PTSD, treatment‑resistant depression, and even H. pylori after a guided MDMA‑psilocybin protocol, highlighting the importance of skilled guidance, post‑session integration, and the “critical period” of heightened neuroplasticity. They contrast MDMA’s empathogenic, body‑anchored effects with psilocybin’s dissociative, mind‑expanding qualities, and discuss how these tools reshape personal parts, improve relational dynamics, reduce addiction drives, and boost peak performance. The episode ends with practical resources, Mike’s neuro‑rewiring programs, and an invitation for listeners to explore psychedelic‑assisted healing responsibly.

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