Beyond Diagnosis

16 Apr 2026 · 32 min

0:00

In this podcast episode, host Rita De Michele interviews sugar‑addiction specialist Mike Collins. Collins explains that while sugar addiction is not yet listed in the DSM, work groups in the DSM and ICD are moving toward formal recognition. He describes how excessive sugar and fructose intake fuels metabolic disorders (fatty liver, type‑2 diabetes, heart disease) and, more recently, a field called metabolic psychiatry that links sugar reduction to remission of depression, bipolar disorder, and improved cognition. The conversation delves into the neurochemical basis of cravings—dopamine, serotonin, norepinephrine, GABA, oxytocin, endorphins—and how these reward pathways operate largely unconsciously, making it hard for people to connect mood swings, irritability, or fatigue to recent sugar consumption. Collins offers practical behavioral tools, notably “pattern interrupts” such as a hand‑clap or snap to break the automatic limbic drive, and stresses the importance of peer‑support groups. He warns that natural sweeteners, fruit, dried fruit, fruit juices, and non‑caloric sweeteners (e.g., stevia) still activate sweetness receptors and perpetuate cravings. For lasting change, he advocates a strict 30‑ to 90‑day total sugar abstinence, arguing that partial cheat days keep cravings alive, whereas full abstinence rewires neural pathways, reduces inflammation, improves joint pain, weight, A1C, and most importantly restores brain clarity, focus, and sleep. The episode concludes with a call to listeners to try a 90‑day detox, highlighting the broader health transformations reported by participants.

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