Richard Johnson, MD: Diabetic Animal Showed Problems with Cognitive Function
Dr. Richard Johnson summarizes research in diabetic laboratory animals showing that chronic sugar exposure is associated with development of Alzheimer's-like brain changes (amyloid and tau), cognitive dysfunction, elevated brain fructose and fructokinase, and mitochondrial/ATP impairment. He reports that inhibiting or knocking down fructokinase rescued ATP levels and reversed the cognitive/phenotypic deficits, implicating fructose metabolism in the observed cognitive dysfunction.
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