Richard Johnson, MD: Fructose Causes Weight Gain in Mice
A YouTube interview/presentation describing an experiment in which mice were given fructose in their drinking water. Initially (first couple of weeks) mice drank the fructose but ate less food and did not gain weight; after several weeks this compensatory regulation broke down, leading to increased calorie intake and reduced resting energy metabolism, causing weight gain and a sedentary-like resting state.
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