Robert Lustig: Even when consuming vitamin D, it does not show in blood test? I do not know why?
Robert Lustig discusses why some people have low circulating 25-hydroxyvitamin D levels despite taking oral vitamin D supplements. He frames it as a conundrum, states he doesn't know the definitive answer, and offers a hypothesis: vitamin D (a prohormone) must be converted in the liver by the 25-hydroxylase enzyme into 25-hydroxyvitamin D, and this conversion may explain the observation.
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