Robert Lustig: Excess Fat Overwhelms the Liver, Leading to Fatty Liver Disease (Hepatic Steatosis)
Robert Lustig explains how choline levels in the liver determine whether fat gets exported or stored. Patients with high choline can export fat through APOB100, while those with low choline accumulate it, causing fatty liver disease. The liver's ability to clear fat depends on this single metabolic switch.
Questions this video answers
Magnetic resonance spectroscopy (MRS).
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