Robert Lustig: How Chronic Stress, Neuropeptide Y, and Diet Drive Metabolic Disease #stress #obesity
25 Jan 2025 · 1 min

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Robert Lustig explains the difference between acute and chronic stress responses: acute stress releases adrenergic signals (norepinephrine) for immediate action, whereas chronic stress additionally releases neuropeptide Y (NPY). He states NPY is co-localized with norepinephrine throughout the body and acts as a brake on the adrenergic system, shifting the chronic response in the opposite direction from the acute response.










