Robert Lustig, MD: cracking the TOFI Code "Thin on the Outside and Fat Inside" #nafld #sugar #tofi
8 Oct 2023 · 1 min

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Excerpt from a talk describing the TOFI phenotype (Thin on the Outside, Fat on the Inside). The speaker contrasts two visually similar adults—one with subcutaneous fat (cosmetic, metabolically inert) and one with intra‑abdominal/visceral fat (metabolically active and sick)—and raises practical questions about identification, clinical recognition, and subsequent action needed to address health and healthcare gaps.










