Robert Lustig, MD: Fructose Alters Intestinal Barrier Integrity
Short excerpt from a YouTube video in which Dr. Robert Lustig states that fructose disrupts intestinal barrier integrity by nitrating tight-junction proteins and depleting ATP in enterocytes (via altered mitochondrial function). This barrier failure may permit bacterial and lipopolysaccharide translocation to the liver, causing hepatic inflammation and insulin resistance.
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