Robert Lustig, MD: Fructose Inhibits 3 Enzymes That Are Responsible for Mitochondrial Function
A short transcript excerpt from a video where the speaker (citing Robert Lustig/related work) explains that fructose inhibits three key enzymes (AMP kinase, long-chain acyl-CoA dehydrogenase, and CPT1A via uric acid), reducing hepatic beta-oxidation and increasing fat storage in the liver; high dietary fructose is therefore harmful to liver and whole-body metabolism independent of caloric load.
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