Robert Lustig, MD: Genetics play a role in Non-Alcoholic Fatty Liver Disease #shorts #sugar #food
7 Oct 2023 · 0 min

0:04
Short transcript discussing genetic contributors to non-alcoholic fatty liver disease (NAFLD), noting that two polymorphisms—PNPLA3 and SLC16A11—common in Latinos increase triglyceride synthesis and conversion of fructose to liver fat, so small amounts of sugar can produce substantial liver fat. The speaker states about 18% of Latinos carry these risk variants.
Questions this video answers
PNPLA3 (patatin-like phospholipase domain containing 3) and SLC16A11.
About 18% of Latinos.
They increase conversion of fructose to liver fat and promote triglyceride synthesis, so small amounts of sugar can produce a lot of liver fat.










