Robert Lustig argues the standard calories-in-calories-out model of obesity misses the biochemistry. Hormones in your liver, brain, and pancreas can force your body to store fat and burn less energy, regardless of willpower. Weight gain isn't just about eating more.
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Remember our first law. Remember our interpretation of the first law. If you eat it, you better burn it or you're going to store it. That's the common wisdom that the weight gain is secondary to two behaviors. There's another interpretation, and the data I've just shown you about Ross says that it goes like this. Instead, if you're going to store it, that is an obligate weight gain set up by biochemical forces out of your control, like, for instance, Ross in the liver or in the brain or in the pancreas. And you expect to burn it because normal energy expenditure equals normal quality of life. Because energy expenditure and quality of life are synonymous. Think about it. Things that increase your energy expenditure make you feel good.