Brief excerpt from a YouTube interview where an interviewer asks Dr. Robert Lustig about the downsides of an extreme ketogenic diet. Lustig responds by characterizing the ketogenic diet itself as already extreme; the segment introduces a discussion about potential downsides to such diets.
What are the downside of extreme ketogenic diet?
Well, ketogenic diet's already extreme.
I know. What is it? What is the potential downside?
Well, so if you have familial hypercholesterolemia, you can't be on a ketogenic diet because you can't process the ldl, because your LDL is going to go up on a ketogenic diet, and you need the LDL receptor to be able to internalize. And if you can't Internalize now, your LDLs are super high and you're gonna get a heart attack and die. So that's one in 500 people. Right. Right off the bat. In addition, there's a disorder called type 5 hyperkylo micronemia. Okay. You can't clear the chylomicrons and you can't be on a ketogenic diet. You have to be on a low fat diet for both of those.