Robert Lustig: There are many more ROS’s from Fructose than Glucose because of its stereochemistry
Robert Lustig explains why fructose generates more reactive oxygen species than glucose: its stereochemistry. Fructose also blocks mitochondrial function at three key points, driving fat storage. In rats lacking methionine and choline, both needed for the liver's antioxidant defenses, fat accumulates in the liver.
Questions this video answers
A methyl group for glutathione (the hepatic antioxidant).
Cofactor for production of phosphatidylcholine, the method for lipid export out of the liver.
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