Video: Biofilm Profiling Services - Minimal Biofilm Eradicating Concentration (MBEC)

Hi, I'm Cameron of Emeryville Pharmaceutical Services and I'm here to talk to you about our biofilm services, including Minimal Biofilm Eradication concentration or mbec. Biofilm can grow nearly everywhere, including riverbeds, high temperature geysers or even in your kitchen sink. Biofilm can even grow on medical devices and implants. It is commonly found on urinary and central venous catheters, pacemakers and artificial heart valves, to name a few. Biofilm is an exopolysaccharide matrix that is formed when a microorganism adheres to a surface. This biofilm serves as a protective barrier that could prevent an antibiotic from killing enclosed bacteria and fungi. The antibiotic is unable to successfully penetrate the biofilm, resulting in antibiotic resistance. The Minimum Biofilm Eradication Concentration EMBEC can be used to determine the efficacy of an antimicrobial agent against biofilm. EMBEC Assay uses a Calgary biofilm device, a 96 well plate with pegs built into the lid that allow for adherence and growth of biofilm. Once biofilm is grown on these pegs, EMBEC can be determined. EMBEC is the minimal concentration necessary to eradicate already formed biofilm. At eps, we also offer Minimal Biofilm Inhibitory concentration or mbic, which is the minimal concentration necessary to inhibit initial biofilm growth. EPS has extensive experience in studies involving biofilm. In addition to MBEC and mbic, we offer a number of other models including CDC Reactor, Drip Flow Reactor, Fully Urinary Catheter Blockage models and can even help with your custom biofilm study needs. Please contact EPS if you are interested in our Biofilm services. For a free one hour consultation, please call us at 510-899-8828. For more information on Biofoam and any of our other services, please visit our website@emorypharmaservices.com.