Ghidul esențial al femeii după 35 de ani | Bun Bine | cu Dr. Călin Todoran

9 Apr 2025 · 90 min
1:29:48

Recorded Bun Bine interview (Romanian) with Dr. Călin Todoran about female physiology after age 35. Main themes: perimenopause is characterised by large hormonal fluctuations that shape later menopause; fertility preservation (AMH testing, egg freezing) is recommended earlier to reduce later stress; gut microbiome (termed "estrabolom") and the enzyme beta‑glucuronidase influence estrogen re‑absorption and hormonal balance; stress/cortisol, diet (diverse plants, limit ultra‑processed foods), sleep and strength training are key modifiable levers; hormone replacement therapy (HRT) — bioidentical options and multiple administration routes — can restore quality of life but requires individualized risk assessment (cardiovascular, thrombotic, cancer considerations). Practical points: AMH/ovarian reserve testing (day 3–5 referenced), AMH threshold "under 1" flagged as concerning; estradiol target window quoted during Q&A (limit of 60 as lower bound; target ~60–100); muscle mass built before mid‑40s protects bone; early menopausal years include rapid bone loss.

Questions this video answers

Referenced as done on day 3–5 of the menstrual cycle.

He stated that if AMH is under 1 the patient should raise a concern about declining/oocyte quality.

He mentioned a lower limit of ~60 and suggested bringing patients between ~60 and 100 (units/context quoted from speaker).

He said the body can lose about >20% of bone in the first five years after menopause.

He referred to a 'window of opportunity' to initiate HRT up to about 10 years after menopause; also discussed benefit of starting earlier during perimenopause.

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