High insulin levels from chronic blood sugar elevation trigger inflammation and excess androgens that damage egg quality and ovarian function. Insulin acts as a growth hormone, promoting visceral fat and systemic inflammation that disrupts the brain hormones controlling reproduction.
Chapters
When you start to have higher glucose levels in your blood your body has to release more insulin. And it's like if this salesman comes to your door every single day, you're going to stop answering it. You know what's happening and that is what insulin resistance is. The cell is no longer opening the door for the salesman and it takes a higher insulin level to get the glucose in the cell. The salesman has to pound on the door really hard to let insulin get into the cell. This is problematic on a couple levels because insulin is known as a growth hormone and high insulin levels are then causing you to store visceral fat. Your cells are actually nutrit but there's so much glucose in your bloodstream this is extremely inflammatory. Impacts how your brain interprets hormones changes your ovarian function directly and makes androgens. More male hormones start to be produced right at the ovarian level. In addition changes how the ovary responds changes egg quality the mitochondrial health right inside the eggs.