Cum poți preveni cancerul colorectal | BOABE DE CUNOAȘTERE | cu Dr. Lucian Negreanu

31 Mar 2025 · 92 min
Episode

31 Mar 2025 · 92 min

0:00

Romanian podcast (recorded Mar 31, 2025) hosted by Dr. Mihail Pautov with Prof. Lucian Negreanu discussing colorectal cancer prevention. Key points: colorectal cancer is the leading cause of cancer mortality in Romania; colonoscopy screening (and removal of adenomas) prevents cancer and can provide long protection (speaker: up to ~20 years); adenoma→carcinoma progression is the dominant pathway (including flat lesions and genetic syndromes such as Lynch); recommended screening discussion begins around age 45–50 with risk stratification by family history and comorbidities; modifiable risks include obesity, smoking, alcohol, sedentary lifestyle, and diet low in fiber—dietary fiber and a diverse microbiome are protective; FIT (fecal immunochemical test) is used as a noninvasive screen (cutoffs vary; speakers mention FIT sensitivity down to ~2 µg Hb/g stool); alternatives (CT colonography, capsule endoscopy) have trade-offs; colonoscopy quality metrics (withdrawal time ≥6 minutes) and adequate bowel prep are crucial; sedation availability and anesthesiology staffing limit access in some regions; symptomatic red flags include visible or occult bleeding and iron-deficiency anemia; oncologic staging and multidisciplinary boards guide treatment; myths such as 'detox' or 'mucoid plaque' lack evidence. The episode emphasizes talk with family doctors, increased national screening activity, and March as colorectal awareness month.

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