Best Of: Love, Lust & Lexapro

7 Dec 2025 · 40 min
Episode

7 Dec 2025 · 40 min

0:00

In this episode of Sex with Emily, Dr. Emily Morse tackles the pervasive problem of sexual dysfunction caused by antidepressants, especially SSRIs and SNRIs like Lexapro, Zoloft, and Effexor. She explains the neurochemical mechanisms (serotonin‑dopamine imbalance) and cites prevalence data (72% desire loss, 83% arousal issues, 42% orgasm difficulty for vulva owners). The show blends scientific background with real‑world listener questions from Sarah, Elle, Gemma, and Courtney, offering personalized advice on how to restore desire while staying on medication. Emily recommends behavioral “hacks” (masturbation, sexy texts, identifying arousal styles), timing of doses, reducing alcohol, low‑dose cannabis, and using toys (Hera rabbit vibrator, Lelo Dot). She outlines pharmacological alternatives (switching to Wellbutrin, Remeron, or non‑SSRI options) and supplements (saffron, 5‑HTP, magnesium). Holistic strategies such as exercise, nutrition, acupuncture, yoga, and magnesium supplementation are discussed. Advanced treatments—including TMS, ketamine, MDMA, psilocybin, and hormone replacement therapy for perimenopausal women—are presented as possible routes when meds fail. Throughout, Emily maintains an empathetic, hopeful tone, encouraging listeners to experiment, consult clinicians, and prioritize both mental health and pleasure.

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