Why Antidepressants Can Kill Your Sex Drive (And What to Do)

29 Aug 2025 · 32 min
Episode

29 Aug 2025 · 32 min

0:00

In this episode of Sex with Emily, host Dr. Emily Morse blends personal wellness promotion, medical education, cultural commentary, and listener call-ins to explore how antidepressants affect sexual desire and function. The show opens with a sponsored endorsement of the Peaklife (PIQUE) hydration protocol, describing a two‑part electrolyte drink routine that claims to boost mood, energy, sleep, and libido. Emily then delves into the pharmacology of antidepressants, explaining why SSRIs and similar drugs often lower libido, impair arousal, and hinder orgasm. She contextualizes these effects with a cultural analysis of Cardi B and Megan Thee Stallion’s “WAP,” discussing myths around female lubrication, the pressure for women to be constantly wet, and the reality that wetness does not equal arousal. The episode provides practical guidance on managing both insufficient and excessive vaginal wetness, emphasizing the role of pelvic‑floor health, Kegel exercises, and the Yarlap electro‑stimulation device. Two listener calls follow. First, April (39, California) shares relationship stress, lack of sexual interest, and practical concerns (pet, moving, future plans). Emily advises that fluctuating desire is normal, recommends open communication, couples therapy, and outlines how unresolved resentment can dampen libido. Second, Olivia (22, Brooklyn) describes SSRI‑induced loss of orgasm and libido while on Prozac. Emily suggests mindfulness, erotic mental engagement, discussing dosage adjustments or switching to Wellbutrin with a physician, and highlights that side effects may lessen over time. A third caller, Colin, reports using Zoloft + Lexapro and switching Lexapro to Wellbutrin, noting restored desire but lingering orgasm difficulty, reinforcing the utility of Wellbutrin for sexual side‑effect mitigation. The episode concludes with a product plug for the Nova 2 vibrator, describing its design and claimed ability to produce blended orgasms, and ends with standard podcast sign‑off and social‑media calls to action.

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